2Ophthalmologist, Gaziantep Children?s Hospital, Gaziantep, Turkey DOI : 10.37845/ret.vit.2021.30.57 Purpose: The objective of the study is to assess the effi ciency of treatment, additional treatment requirements and results of additional treatments in infants who underwent laser photocoagulation (LP) due to retinopathy of prematurity (ROP).
Materials and Methods: This two-center, retrospective trial evaluated the treatment results of preterm infants who underwent LP for ROP between 2013 and 2019 and who were also followed for at least 1 year following LP.
Results: Four hundred thirty-seven eyes of 225 infants were included in the study. Of the eyes treated with LP, 284 had type 1 ROP, 129 had type 2 ROP, and the remaining 24 eyes had aggressive posterior retinopathy of prematurity (APROP). After the initial LP, manifestations of ROP regressed completely in 397 (90.8%) eyes, whereas for 40 eyes (9.2%), additional treatment was required. Of these infants, 18 (45%) eyes underwent rescue intravitreal bevacizumab (IVB), while LP was applied at the posterior ridge of 16 (40%) eyes, and additional LP was applied in 6 (15%) eyes. Fourteen (58.3%) eyes with APROP and 26 (9.2%) eyes with type 1 ROP required additional treatments, and the difference between them was statistically signifi cant (p<0.001). After all follow-up and treatments, an unfavourable anatomic outcome was observed in 4 eyes (0.9%) at a corrected age of one year.
Conclusion: Near-confl uent LP is an effi cient treatment, in particular for infants with type 1 and type 2 ROP. However, the requirement of additional treatment following the initial LP is greater in infants with APROP.
Keywords : Aggressive posterior retinopathy of prematurity (APROP), Type 1 retinopathy of prematurity (ROP), Type 2 retinopathy of prematurity, Laser photocoagulation (LP)