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¹İzmir Katip Çelebi Üniversitesi, Atatürk Eğitim ve Araştırma Hastanesi Göz Kliniği, İzmir
²İzmir Katip Çelebi Üniversitesi Göz Hastalıkları Anabilimm Dalı, İzmir We aimed to evaluate the clinical features and treatment results in 4 cases with Vogt-Koyanagi-Harada syndrome (VKH). Four female cases?age range was 33-58 years, follow-up duration 8 to 49 months. All cases had bilateral involvement. Auditory complaints were available in three cases (hearing loss in 1 case, tinnitus in 2 cases). All cases were assessed by spectral domain optical coherence tomography, fl uorescein angiography and ultrasonography. Three patients were classified as \"incomplete VKH\" and one as \"probable VKH?. Baseline visual acuity ranged from 2/20 to 3/20 in the RE and from 2/20 to 4/20 in the LE. All cases had bilateral anterior uveitis and exudative retinal detachment. Optic disc edema was also present in three cases. All patients were treated with high-dose corticosteroid therapy. In addition, cyclosporine was administered to two cases and azathioprine to one case. Final visual acuity ranged from light perception to 20/20 in the RE and from 12/20 to 20/20 in the LE. During the follow-up, recurrence was observed twice in 1 case; choroidal neovascular membrane in 1 case, pupillary block, neovascular glaucoma and cataract in 1 case and secondary glaucoma in 1 case. Visual loss could be prevented by early diagnosis and treatment in VKH patients. Corticosteroid is eff ective in treatment of VKH. Immunosuppressive drugs could be useful in patients with a chronic VKH refractory to corticosteroid or who suff er severe adverse eff ects with corticosteroid. VKH cases should be followed closely with regard to possible complications and recurrence. Keywords : Immunosuppressive drugs; optical coherence tomography; steroid; uveitis; Vogt-Koyanagi-Harada syndrome