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¹M.D. Associate Professor, Celal Bayar University Faculty of Medicine, Department of Ophthalmology, Manisa/TURKEY
²M.D. Asistant Professor, Celal Bayar University Faculty of Medicine, Department of Ophthalmology, Manisa/TURKEY
³M.D. Professor, Celal Bayar University Faculty of Medicine, Department of Ophthalmology, Manisa/TURKEY In this case report, we presented a 52 year old female patient suffering from decreased vision in her left eye approximately for 1 month. She was diagnosed with left branch retinal vein occlusion (BRVO) after ophthalmologic evaluation. She then developed right BRVO approximately 8 months after the left eye. Methylenetetrahydrofolate reductase C677T homozygote gene mutation, plasminogen activator inhibitör-1 heterozygote gene mutation with factor V H1299R heterozygote gene mutation were detected on genetic analysis. The patint was then diagnosed with hereditary thrombophilia and started anticoagulant therapy. Her left eye was treated with a combination of anti vascular endothelial growth factor (anti-VEGF) agents while her right eye was treated with a combination of anti- VEGF and intravitreal dexamethasone implant successfully. It might be important to consider the thrombophilic factors especially in bilateral cases, though the effect of thrombophilic factors in etiopathogenesis of BRVO is controversial. Keywords : Branch retinal vein occlusion, hereditary thrombophilia, thrombophilic risk factors